Holding(s) in Company

8th January 2010 REGEN THERAPEUTICS PLC (?ReGen? or the ?Company?; Ticker: (RGT)) TR-1(i): NOTIFICATION OF MAJOR INTEREST IN SHARES 1. Identity of the issuer or the ReGen Therapeutics Plc underlying issuer of existing shares to which voting rights are attached (ii): 2. Reason for the notification: An acquisition or disposal of   voting rights 3. Full name of person(s) subject to the Andrew Clement Wilson notification obligation (iii): 4. Full name of shareholder(s) (if As Above difference from 3): 5. Date of the transaction and date on 7th January 2010 which the threshold is crossed or reached (v): 6. Date on which issuer notified: 8th January 2010 7. Threshold(s) that is/are crossed or 5% reached: 8. Notified details A: Voting rights attached to shares Class/type of share if possible using the GB00B28XMY25 ISIN Code Situation Previous to the triggering transaction (vi) ? Number of Shares 2,590,000 Number of Voting Rights (viii) 2,590,000 Resulting situation after the triggering transaction (viii) ? Number of Shares 1,527,000 Number of Voting Rights ? Direct (x) 1,527,000 Number of Voting Rights ? Indirect (xi) N/A % of voting rights ? Direct 4.157% % of voting rights ? Indirect N/A B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of financial instrument N/A Expiration date (xiii) N/A Exercise/Conversion Period/Date (xiv) N/A Number of voting rights that may be N/A acquired if the instrument is exercised/converted % of voting rights N/A C: Financial Instruments with similar economic effect to Qualifying Financial Instruments Resulting situation after the triggering transaction Type of financial instrument N/A Exercise Price N/A Expiration Date N/A Exercise Conversion Period N/A Number of voting rights N/A Instrument refers to % of voting rights N/A Total (A+B+C) Number of voting rights 1,527,000 % of voting rights 4.157 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable (xv): Proxy Voting: 10. Name of the proxy holder: Wapole St Andrews Nominee 11. Number of voting rights proxy holder N/A will cease to hold: 12. Date on which proxy holder will cease N/A to hold voting rights: 13. Additional information: N/A 14. Contact name: Patrick Wilson 15. Contact telephone number: 028 90 434040 For further information: For further information, please contact: Percy Lomax ReGen Therapeutics Plc Tel: 020 7153 4920 Roland Cornish/Felicity Geidt Beaumont Cornish Limited Tel: 020 7628 3396 David Scott /Nick Bealer Alexander David Securities Limited Tel: 020 7448 9800 [HUG#1371846]