Positive biotech sector momentum continues - transformational new products the key driver
BB BIOTECH AG /
Positive biotech sector momentum continues - transformational new products the
key driver
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BB Biotech proposes a tax-efficient cash distribution of CHF 7.00 per share
The Nasdaq Biotech Index advanced another 8.3% (in USD) in the fourth quarter,
crowning 2013 as one of the best years ever for biotech stocks. Both the top
holdings and the more recently established midcap positions in BB Biotech's
portfolio performed well. The investment company's shares ended the year with a
fourth quarter performance of 10.4% (in CHF) and an annual performance of 66%
(in CHF) - 5 percentage points more than the benchmark index. These excellent
gains are fundamentally sound and driven in part by new product launches such as
Actelion's Opsumit for pulmonary arterial hypertension and Gilead's Sovaldi for
hepatitis C. Keeping the payout policy established in 2013, the Board of
Directors will propose a cash distribution of CHF 7.00 per share at the upcoming
annual general meeting corresponding to a yield of 5%.
Positive biotech sector momentum continues
The strong upward trend of the biotech sector continued in the fourth quarter of
2013 with the Nasdaq Biotech Index (NBI) gaining 8.3% (in USD), performing in
line with the broader S&P 500 Index, which gained 10.5% in the same time. For
the 12 months of 2013, the NBI gained 66.0%, twice that of the S&P index (all
values in USD including dividends).
The continued upward move in the fourth quarter was driven by important product
approvals, further progress of key clinical programs and strong third quarter
2013 financial results supporting the strong industry growth trajectory and
commensurate valuations.
BB Biotech performance for the fourth quarter and 12 months 2013
BB Biotech's performance was driven by growth across the portfolio, both by long
term holdings and by midcap holdings that have been built more recently.
The share price of BB Biotech once more increased by double digits in the fourth
quarter 2013 - adding 10.4% in CHF. The positive fourth quarter contributed to
the 12 month 2013 share price appreciation of 66.0% in CHF, 65.6% in EUR and
70.2% in USD, including the cash distribution of CHF 4.50.
In the fourth quarter, the Net Asset Value (NAV) increased 5.2% in CHF, 4.8% in
EUR and 6.6% in USD - and for the 12 month 2013, the NAV significantly increased
77.0% in CHF, 74.1% in EUR and 81.4% in USD (all values account for the cash
distribution of CHF 4.50 per share).
Proposed cash distribution for the fiscal year 2013 of CHF 7.00 per share
In line with the distribution policy established in 2013, the board will propose
a tax-efficient cash distribution of CHF 7.00 per share following the Annual
General Meeting (AGM) on March 19th, 2014, applying a 5% yield to the weighted
volume average share price in December 2013. Going forward, the cash
distribution will be calculated the same way.
BB Biotech continued its share repurchase program in the fourth quarter
acquiring 130'000 shares through the second trading line for a total CHF 17.8
mn. For 2013, a total of 415'000 shares, of the 1'185'000 approved at the AGM on
March 18, 2013, were repurchased. The difference between book value and share
price nevertheless widened over the year and the program will continue as
planned.
Despite the fundamentally strong sector growth and the above average performance
of BB Biotech the structured distribution policy will be continued consequently
to return capital to the shareholders of 10%.
Changes to the team in 2013
In March 2013, Dr. Erich Hunziker became the new Chairman of BB Biotech, after
joining the company's board two years ago. Prof. Dr. med. Thomas Szucs did not
stand for re-election after ten years of successful chairmanship and board
membership. BB Biotech's shareholders elected Prof. Dr. Dr. Klaus Strein as new
board member of the company.
In the fourth quarter, BB Biotech increased its portfolio management team by one
member, adding expertise in the central nervous system (CNS) disease category.
With a continued high unmet medical need in many disorders such as Alzheimer,
schizophrenia and depression, BB Biotech will research companies to identify
potential investment candidates in these areas.
Existing portfolio continues to perform well driven by transformational new
products reaching the market
The fourth quarter performance was driven by further key product approvals for
important BB Biotech holdings:
* Sovaldi (Gilead), a first in class nucleotide analog polymerase inhibitor
for the treatment of hepatitis C Virus (HCV) infected patients, in
combination with ribavirin for HCV genotype 2 and genotype 3 infected
patients, and in combination with peg-interferons and ribavirin for the
treatment of HCV genotype 1 infected patients
* Opsumit (Actelion), a novel endothelin receptor antagonist (ERA) for the
treatment of PAH, with a differentiated product label compared to the
currently marketed ERAs
* Imbruvica (Pharmacyclics), a bruton's tyrosine kinase inhibitor for the
treatment of patients with mantle cell lymphoma (MCL) who have received at
least one prior therapy
Key clinical data from Celgene's MM-020 clinical study were presented in mid-
December 2013 at the American Society of Hematology (ASH) supporting our
projection of significant use of Revlimid in newly diagnosed multiple myeloma
patients.
In addition to the strong performing large cap positions, Incyte has become a
considerable position from the midcap space. The failure of a key JAK competitor
in late clinical development, lower competitive pressure for the company and
focus on other pipeline opportunities all led to stock price appreciation for
Incyte. Important Phase III results are expected in early 2014 for polycythemia
vera (PV) patients potentially expanding further the revenue potential for
Jakafi. With Incyte and Isis BB Biotech's portfolio now has grown two core
positions in the midcap biotech space, as their valuation appreciated in 2013.
Smaller adjustments in the fourth quarter of 2013 in a well performing portfolio
In the fourth quarter of 2013, turn-over in investments was lower than earlier
in the year. The most significant changes to the portfolio were additions to our
positions in Pharmacyclics (2.8% of the portfolio), Synageva (2.3%), Regeneron
(2.2%) and Neurocrine (1.0%). To finance these acquisitions, we used cash
profits from our successful investments in longer term large- and midcap
holdings such as Isis, Incyte and Halozyme. Ariad showed a modest recovery in
share price following the market re-introduction of Iclusig. This enabled us to
reduce our Ariad holding. The management team sold the holdings in Optimer which
was acquired by Cubist. We also sold our position in Valneva.
Outlook
The continued success of BB Biotech will be based on thoughtful, rigorous
selection to identify new medications with the potential of becoming innovative
standards of care. Assets demonstrating such innovation recently have included
the novel single tablet regiment for the treatment of HIV, the IMiDs, such as
Revlimid for the treatment of multiple myeloma, or novel oral agents such as
Tracleer for the treatment of pulmonary arterial hypertension (PAH).
With the recent approval of Sovaldi, we expect a dramatic change in the
treatment paradigm for HCV patients. Sovaldi and Gilead's HCV franchise success
are expected to be a key driver for further fund flow momentum for the biotech
industry as a whole. We would highlight Xtandi for the treatment of prostate
cancer, Imbruvica for lymphoma indications such as CLL and NHL and Opsumit for
the treatment of PAH as some of the recent product approvals that have
blockbuster potential and will help drive the industry higher.
Furthermore, new orphan drugs are in late stage clinical development to address
rare and severe diseases. Another important area of significant investment for
BB Biotech are the platform technologies, such as the RNA based medicines
(antisense and RNAi), antibody drug conjugates, small molecule drug conjugates
as well as novel delivery approaches for current intravenously administered
biologics.
2014 will be another exciting biotech year with many key clinical trial results,
further significant product approvals, and possible consolidation in the sector
to continue.
Despite a rerating observed during the last two years, BB Biotech believes the
sector remains attractively valued. Pipelines continue to deliver innovative
products, and fundamentals remain strong. BB Biotech continues to expect the
sector to perform strongly and to deliver double digit returns to investors.
The webcast with Dr. Daniel Koller, Head Management Team BB Biotech, is
available on www.bbbiotech.com. The complete annual report as of December
31, 2013 will be published on February 20, 2014.
For further information:
Investor Relations
Bellevue Asset Management AG, Seestrasse 16, 8700 Küsnacht, Switzerland, tel.
+41 44 267 67 00
Dr. Silvia Schanz, ssc@bellevue.ch
Maria-Grazia Iten-Alderuccio, mga@bellevue.ch
Claude Mikkelsen, cmi@bellevue.ch
Media Relations
b-public AG, Pfingstweidstrasse 6, 8005 Zürich, Switzerland, tel.
+41 79 423 22 28
Thomas Egger, teg@b-public.ch
Bellevue Asset Management AG, Seestrasse 16, 8700 Küsnacht, Switzerland, tel.
+41 44 267 67 00
Tanja Chicherio, tch@bellevue.ch
www.bbbiotech.com
Company profile
BB Biotech invests in companies in the fast growing market of biotechnology and
is one of the world's largest investors in this sector with more than CHF 2.1
billion in assets under management. BB Biotech is listed in Switzerland, Germany
and Italy. Its investments are focused on listed companies that are developing
and commercializing novel medical treatments and cures. BB Biotech's investment
selection process is guided by the fundamental research and analysis of
physicians and molecular biologists. Its Board of Directors has many years of
experience in industry and science.
Disclaimer
This release contains forward-looking statements and expectations as well as
assessments, beliefs and assumptions. Such statements are based on the current
expectations of BB Biotech, its directors and officers, and are, therefore,
subject to risks and uncertainties that may change over time. As actual
developments may significantly differ, BB Biotech and its directors and officers
accept no responsibility in that regard. All forward-looking statements included
in this release are made only as of the date of this release and BB Biotech and
its directors and officers assume no obligation to update any forward-looking
statements as a result of new information, future events or other factors.
Composition of BB Biotech's portfolio as of December 31, 2013
(in % of securities, rounded values)
Celgene  14.1%
Actelion  11.7%
Gilead  11.0%
Isis Pharmaceuticals  10.5%
Incyte  8.8%
Vertex Pharmaceuticals  4.3%
Alexion Pharmaceuticals  4.1%
Medivation  3.9%
Novo Nordisk  3.5%
Halozyme Therapeutics  2.9%
Pharmacyclics  2.8%
Swedish Orphan Biovitrum  2.7%
Synageva BioPharma  2.3%
Regeneron Pharmaceuticals  2.2%
Immunogen  1.9%
Theravance  1.3%
Glenmark Pharmaceuticals  1.3%
Alnylam Pharmaceuticals  1.2%
Clovis Oncology  1.2%
Endocyte  1.2%
Lupin  1.1%
Neurocrine Biosciences  1.0%
Ipca Laboratories  0.9%
Bavarian Nordic  0.8%
Infinity Pharmaceuticals  0.7%
Radius Health (1) ) Â 0.6%
Tesaro  0.5%
Ariad Pharmaceuticals  0.4%
Idenix Pharmaceuticals  0.3%
Probiodrug (1)) Â 0.3%
Achillion Pharmaceuticals  0.2%
Strides Arcolab  0.1%
Cubist Pharmaceuticals Contingent Value Rights- ex Trius  0.0%
Cubist Pharmaceuticals Contingent Value Rights- ex Optimer  <0.1%
Radius Health Warrants  0.0%
Total securities  CHF 2 167.2 mn
Other assets  CHF 43.7 mn
Other payables  CHF (92.0) mn
Total shareholder's equity  CHF 2 118.9 mn
Treasury shares (in % of company) (2) Â 3.9%
1) Unlisted company
2) Correspond to the total of all own shares held including the second trading
line
Media Release_23.01.2014 (PDF):
http://hugin.info/130285/R/1756424/593162.pdf
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Source: BB BIOTECH AG via GlobeNewswire
[HUG#1756424]