ABLYNX RAISES ¤75 MILLION IN SUCCESSFUL IPO - Largest ever biotech IPO on Euronext Brussels

THIS ANNOUNCEMENT IS NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN OR INTO THE UNITED STATES, CANADA, JAPAN AND AUSTRALIA FOR IMMEDIATE RELEASE 6 November 2007 GHENT, Belgium - 6 November 2007 - Ablynx, the biopharmaceutical company focused on the discovery and development of Nanobodies®, announced today that it has successfully completed its initial public offering (IPO) and will be listed as of tomorrow on Eurolist by Euronext Brussels under the symbol "ABLX". The IPO was priced at ¤7.00 per share. Pursuant to the offering, 10,714,285 new shares, equivalent to ¤75.00 million, will be issued by Ablynx, and additionally, 1,607,142 over-allotment shares, equivalent to ¤11.25 million will be allocated. If the over-allotment option is exercised in full, the total amount of the capital increase will amount to ¤86.25 million. J.P. Morgan Securities Ltd. and KBC Securities NV acted as Joint Global Coordinators and Joint Bookrunners, with Kempen & Co N.V. and Piper Jaffray Ltd acting as Co-Managers to the offering. Commenting on today's announcement, Dr Edwin Moses, Ablynx's Chairman and Chief Executive Officer, said: "We are delighted to have successfully completed our IPO and to have been able to secure the interest of high quality institutional investors. I view this positive outcome as a reflection of the strength of our Nanobody® platform and pipeline and our investors' confidence in Ablynx's growth prospects. We intend to use the funds raised to rapidly move forward with our lead programme ALX-0081 currently in Phase I, and quickly build a strong clinical pipeline with truly innovative Nanobody-based therapeutics across multiple therapeutic areas where there is a large unmet medical need, thus creating value for our shareholders." Offer highlights - The final IPO price was set at ¤7.00 per share and applies to both retail and institutional investors. - The base offering was approximately one and a half times subscribed. - Retail investors will be allocated 10% of the total number of allotted shares or 1,232,143 shares. Within the retail tranche, ¤300,000 in shares will be allotted on a preferential basis to the Company's employees, consultants and independent directors. The shares for retail investors will be allotted according to the allocation table below. All these shares are new shares with VVPR-strips.